About Us

The concept of iFormulate was developed at HTD Biosystems.  In formulating many proteins, an efficient high throughput algorithm was designed to perform preformulation of proteins in a rational fashion using Design of Experiments (DOE) and multivariate analysis.

History of iFormulate™

We designed a multivariate statistical experimental design to evaluate the 4 key variables in any protein formulation; pH, ionic strength, buffer concentration, and stabilizer concentration.  The design is a more advanced response-surface design rather than a simple screening design.
This concept has been tested on a number of proteins including antibodies using a number of analytical assays.